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Journal Club

Circadian rhythm heterogeneity modulates drug response variations in neuroblastoma models

Presenter: Buse Avcı

March 9, 2026

Phosphorylation-dependent STAMBP drives the progression of pancreatic ductal adenocarcinoma by deubiquitinating and stabilizing BAG3

Presenter: Betül OruçoÄŸlu

Feb 19, 2026

Combinatorial treatment of glioblastoma with temozolomide (TMZ) plus 5-ethynyl-2′-deoxyuridine (EdU)

Presenter: Dilan Kutlay

Feb 3, 2026

A mouse circadian proteome atlas

Presenter: Selahattin AydoÄŸan

Jan 20, 2026

Overcoming the undruggable barrier: Structure-guided discovery of a potent small molecule CD28 antagonist with translational potential

Presenter: AyÅŸenur Çakmak

Jan 5, 2026

A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms

Presenter: Buse Avcı

Dec 15, 2025

BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinoma

Presenter: Betül OruçoÄŸlu

Dec 1, 2025

Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis

Presenter: Dilan Kutlay

Nov 10, 2025

PBAF/cBAF reorganization on H3.3 chromatin regulates BMAL1 activity in the absence of circadian negative feedback

Presenter: Selahattin AydoÄŸan

Oct 28, 2025

AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor

Design and validation of the first-in-class PROTACs for targeted degradation of the immune checkpoint LAG-3

Presenter: AyÅŸenur Çakmak

Oct 13, 2025

Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption

Presenter: Ece Nihal Sözmen

Oct 7, 2025

Involvement of circadian clock protein PER2 in controlling sleep deprivation induced HMGB1 up-regulation by targeting p300 in the cortex

Presenter: Buse Avcı

Sept 11, 2025

XXX

Presenter: DoÄŸa CanımoÄŸlu

Aug 21, 2025

XXX

Presenter: Berra DoÄŸan

Aug 21, 2025

Deciphering specity and cross-reactivity in tachykinin NK1 and NK2 receptors

Presenter: Zeyneb Mustafa

Aug 20, 2025

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